团队负责人

undefined

丛志奇

研究员

博士生导师

单碳酶催化研究组负责人




简历

2016年至今 中国科学院青岛生物能源与过程研究所 单碳酶催化研究组负责人 

2013年-2016年  日本名古屋大学     研究员

2009年-2013年  日本分子科学研究所  博士研究员

2006年-2009年  日本熊本大学      获理学博士学位

学术经历

丛志奇研究员先后在日本分子科学研究所和名古屋大学从事金属酶及其相关领域的研究工作。在氯过氧化物酶、髓过氧化物酶、及细胞色素P450单加氧酶的分子机理与人工催化应用体系开发方面做出国际水平的成果。在包括JACS, Angew Chem,ACS Catal等国际权威学术杂志发表论文二十余篇,相关成果被ChemistryViews等科学媒体作为亮点报道。担任多个国际期刊审稿人(Tetrahedron/Tetrahedron Lett,2012, TOP10最佳审稿人奖)。2015年任第17次国际生物无机化学会议"金属蛋白和金属酶"分会主席。

获奖和荣誉

2018年    入选青岛市创新领军人才

代表性文章

2016年至今

1. Zhao, Panxia; Chen, Jie; Ma, Nana; Chen, Jingfei; Qin, Xiangquan; Liu, Chuanfei Yao, Fuquan; Yao, Lishan; Jin, Longyi and Cong, Zhiqi*. Enabling Highly (R)-Enantioselective Epoxidation of Styrene by Engineering Unique Non-Natural P450 Peroxygenases. Chem. Sci., 2021, https://doi.org/10.1039/D1SC00317H

2. Jiang, Yihui; Wang, Chunlan; Ma, Nana; Chen, Jie; Liu, Chuanfei; Wang, Fang; Xu, Jiakun*; Cong, Zhiqi*. Regioselective aromatic: O-demethylation with an artificial P450BM3 peroxygenase system, Catalysis Science & Technology, 2020, 10(5): 1219-1223.

3. Chen, Jie; Kong,Fanhui; Ma, Nana; Zhao, Panxia; Liu, Chuanfei; Wang, Xiling; Cong, Zhiqi*. Peroxide-Driven Hydroxylation of Small Alkanes Catalyzed by an Artificial P450BM3 Peroxygenase System. ACS Catal. 2019, 9, 7350-7355.

4. Xu, Jiakun; Wang, Chunlan; Cong, Zhiqi*. Strategies for Substrate-Regulated P450 Catalysis: From Substrate Engineering to Co-catalysis. Chem. Eur. J. 2019, 9, 25, 6853–6863.

5. Ma, Nana; Chen, Zhifeng; Chen, Jie; Chen, Jingfei; Wang, Cong; Zhou, Haifeng;Yao, Lishan; Shoji, Osami; Watanabe, Yoshihito; Cong, Zhiqi*. Dual-Functional Small Molecules for Generating an Efficient Cytochrome P450BM3 Peroxygenase. Angew. Chem. Int. Ed. 2018, 57, 7628-7633.

2011-2015

6. Cong, Zhiqi; Shoji, Osami; Kasai, Chie; Kawakami, Norifumi; Sugimoto, Hiroshi; Shiro, Yoshitsugu; Watanabe, Yoshihito. Activation of Wild-type Cytochrome P450BM3by the Next Generation Decoy Molecules: Enhanced Hydroxylation of Gaseous Alkanesand Crystallographic Evidence. ACS Catal. 2015, 5, 150-156.

7. Cong, Zhiqi; Sachiko, Yanagisawa; Kurahashi, Takuya; Takashi, Ogura; Satoru, Nakashima; Fujii, Hiroshi. Synthesis, Charaterizationand Reactivity of Hypochloritoiron(III) Porphyrin Complexes. J. Am. Chem. Soc. 2012, 134, 20617-20620.

8. Cong, Zhiqi; Kurahashi, Takuya; Fujii, Hiroshi. Formation of Iron(III) meso-Chloro- Isoporphyrinas a Reactive Chlorinating Agent from Oxo-iron(IV) Porphyrin π-Cation Radical. J. Am. Chem. Soc. 2012, 134, 4469-4472.

9. Cong, Zhiqi; Kurahashi, Takuya; Fujii, Hiroshi. Oxidation of Chloride Ion and Subsequent Chlorination of Organic Compounds by Oxoiron(IV) Porphyrin π-CationRadical Complexes. Angew. Chem. Int. Ed. 2011, 50, 9935-9939.


 

CopyRight 2018. 中国科学院青岛生物能源与过程研究所 单碳酶催化研究组 版权所有 All Rights Reserved.地址:山东省青岛市崂山区松岭路189号      联系电话:0532-80662758    邮箱:congzq@qibebt.ac.cn